Sao Tome and Principe’s national health system is facing some problems that hamper the effective performance of its mission to promote public health and the population’s physical and mental well-being and to guarantee healthcare for all its citizens. The health sector is characterized by insufficient health infrastructures, low quality service delivery, insufficient human resources poorly distributed throughout the country and with little motivation, and not enough specialists in various areas. In addition, access to healthcare is very uneven depending on region.